Alonzi, Dominic : rechercher sur Z-Library

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1

Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain

Ardes-Guisot, Nicolas, Alonzi, Dominic S., Reinkensmeier, Gabriele, Butters, Terry D., Norez, Caroline, Becq, Frédéric, Shimada, Yousuke, Nakagawa, Shinpei, Kato, Atsushi, Blériot, Yves, Sollogoub, Ma

Journal:

Organic & Biomolecular Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.88 MB

english, 2011

2

C -Branched Iminosugars: α-Glucosidase Inhibition by Enantiomers of isoDMDP, isoDGDP, and isoDAB– l -isoDMDP Compared to Miglitol and Miglustat

Jenkinson, Sarah F., Best, Daniel, Saville, A. Waldo, Mui, James, Martínez, R. Fernando, Nakagawa, Shinpei, Kunimatsu, Takahito, Alonzi, Dominic S., Butters, Terry D., Norez, Caroline, Becq, Frederic,

Journal:

Journal of Organic Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2013

3

Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins

Alonzi, Dominic S., Kukushkin, Nikolay V., Allman, Sarah A., Hakki, Zalihe, Williams, Spencer J., Pierce, Lorna, Dwek, Raymond A., Butters, Terry D.

Journal:

Cellular and Molecular Life Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2013

4

A Novel Iminosugar UV-12 with Activity against the Diverse Viruses Influenza and Dengue (Novel Iminosugar Antiviral for Influenza and Dengue)

Warfield, Kelly, Plummer, Emily, Alonzi, Dominic, Wolfe, Gary, Sampath, Aruna, Nguyen, Tam, Butters, Terry, Enterlein, Sven, Stavale, Eric, Shresta, Sujan, Ramstedt, Urban

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2015

5

Synthesis and Biological Characterisation of Novel N-Alkyl-Deoxynojirimycin α-Glucosidase Inhibitors

Amy J. Rawlings, Hannah Lomas, Adam W. Pilling, Marvin J.-R. Lee, Dominic S. Alonzi, J. S. Shane Rountree, Sarah F. Jenkinson, George W. J. Fleet, Raymond A. Dwek, John H. Jones, Terry D. Butters

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 214 KB

english, 2009

6

Carbasugar–thioether pseudodisaccharides related to N-glycan biosynthesis

Ian Cumpstey, Dominic S. Alonzi, Terry D. Butters

Journal:

Carbohydrate Research

Année:

2009

Langue:

english

Fichier:

PDF, 368 KB

english, 2009

7

4-C-Me-DAB and 4-C-Me-LAB—enantiomeric alkyl-branched pyrrolidine iminosugars—are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group

Filipa P. da Cruz, Scott Newberry, Sarah F. Jenkinson, Mark R. Wormald, Terry D. Butters, Dominic S. Alonzi, Shinpei Nakagawa, Frederic Becq, Caroline Norez, Robert J. Nash, Atsushi Kato, George W.J.

Journal:

Tetrahedron Letters

Année:

2011

Langue:

english

Fichier:

PDF, 819 KB

english, 2011

8

Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells

Terry D. Butters, Dominic S. Alonzi, Nikolay V. Kukushkin, Yuan Ren, Yves Blériot

Journal:

Glycoconjugate Journal

Année:

2009

Langue:

english

Fichier:

PDF, 237 KB

english, 2009

9

Improved cellular inhibitors for glycoprotein processing α-glucosidases: biological characterisation of alkyl- and arylalkyl-N-substituted deoxynojirimycins

Dominic S. Alonzi, Raymond A. Dwek, Terry D. Butters

Journal:

Tetrahedron: Asymmetry

Année:

2009

Langue:

english

Fichier:

PDF, 405 KB

english, 2009

10

Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo

Jinhong Chang, Wouter Schul, Terry D. Butters, Andy Yip, Boping Liu, Anne Goh, Suresh B. Lakshminarayana, Dominic Alonzi, Gabriele Reinkensmeier, Xiaoben Pan, Xiaowang Qu, Jessica M. Weidner, Lijuan W

Journal:

Antiviral Research

Année:

2011

Langue:

english

Fichier:

PDF, 799 KB

english, 2011

11

Towards a stable noeuromycin analog with a d-manno configuration: Synthesis and glycosidase inhibition of d-manno-like tri- and tetrahydroxylated azepanes

Julia Deschamp, Martine Mondon, Shinpei Nakagawa, Atsushi Kato, Dominic S. Alonzi, Terry D. Butters, Yongmin Zhang, Matthieu Sollogoub, Yves Blériot

Journal:

Bioorganic & Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 917 KB

english, 2012

12

Synthesis and α-Glucosidase II inhibitory activity of valienamine pseudodisaccharides relevant to N-glycan biosynthesis

Ian Cumpstey, Clinton Ramstadius, K. Eszter Borbas, Dominic S. Alonzi, Terry D. Butters

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 405 KB

english, 2011

13

Hydrophilic interaction liquid chromatography of anthranilic acid-labelled oligosaccharides with a 4-aminobenzoic acid ethyl ester-labelled dextran hydrolysate internal standard

David C.A. Neville, Dominic S. Alonzi, Terry D. Butters

Journal:

Journal of Chromatography A

Année:

2012

Langue:

english

Fichier:

PDF, 472 KB

english, 2012

14

Cystic fibrosis and diabetes: isoLAB and isoDAB, enantiomeric carbon-branched pyrrolidine iminosugars

Daniel Best, Sarah F. Jenkinson, A. Waldo Saville, Dominic S. Alonzi, Mark R. Wormald, Terry D. Butters, Caroline Norez, Frederic Becq, Yves Blériot, Isao Adachi, Atsushi Kato, George W.J. Fleet

Journal:

Tetrahedron Letters

Année:

2010

Langue:

english

Fichier:

PDF, 451 KB

english, 2010

15

Fleetamine (3-O-α-d-glucopyranosyl-swainsonine): the synthesis of a hypothetical inhibitor of endo-α-mannosidase

Tim Quach, Sammi Tsegay, Andrew J. Thompson, Nikolay V. Kukushkin, Dominic S. Alonzi, Terry D. Butters, Gideon J. Davies, Spencer J. Williams

Journal:

Tetrahedron: Asymmetry

Année:

2012

Langue:

english

Fichier:

PDF, 716 KB

english, 2012

16

Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses

Chang, Jinhong, Warren, Travis K., Zhao, Xuesen, Gill, Tina, Guo, Fang, Wang, Lijuan, Comunale, Mary Ann, Du, Yanming, Alonzi, Dominic S., Yu, Wenquan, Ye, Hong, Liu, Fei, Guo, Ju-Tao, Mehta, Anand, C

Journal:

Antiviral Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2013

17

Engineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal Antibodies

Yu, Xiaojie, Baruah, Kavitha, Harvey, David J., Vasiljevic, Snezana, Alonzi, Dominic S., Song, Byeong-Doo, Higgins, Matthew K., Bowden, Thomas A., Scanlan, Christopher N., Crispin, Max

Journal:

Journal of the American Chemical Society

Année:

2013

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2013

18

An iminosugar with potent inhibition of dengue virus infection in vivo

Perry, Stuart T., Buck, Michael D., Plummer, Emily M., Penmasta, Raju A., Batra, Hitesh, Stavale, Eric J., Warfield, Kelly L., Dwek, Raymond A., Butters, Terry D., Alonzi, Dominic S., Lada, Steven M.,

Journal:

Antiviral Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2013

19

Non-specific accumulation of glycosphingolipids in GNE myopathy

Patzel, Katherine A., Yardeni, Tal, Le Poëc-Celic, Erell, Leoyklang, Petcharat, Dorward, Heidi, Alonzi, Dominic S., Kukushkin, Nikolay V., Xu, Bixue, Zhang, Yongmin, Sollogoub, Matthieu, Blériot, Yves

Journal:

Journal of Inherited Metabolic Disease

Année:

2014

Langue:

english

Fichier:

PDF, 967 KB

english, 2014

20

Bypass of Quality Control in Protein Folding Pathways Induces Specific Misfolding of HIV Envelope V2 Loop: Implications for Iminosugars as Antivirals

Spiro, Simon, McCaul, Nicholas, Derking, Ronald, Alonzi, Dominic, Dwek, Raymond, Sanders, Rogier, Braakman, Ineke, Zitzmann, Nicole

Journal:

AIDS Research and Human Retroviruses

Année:

2014

Langue:

english

Fichier:

PDF, 63 KB

english, 2014

21

Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4

Warfield, Kelly L., Plummer, Emily M., Sayce, Andrew C., Alonzi, Dominic S., Tang, William, Tyrrell, Beatrice E., Hill, Michelle L., Caputo, Alessandro T., Killingbeck, Sarah S., Beatty, P. Robert, Ha

Journal:

Antiviral Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2016

22

Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum α-glucosidase inhibition

Alonzi, Dominic S., Neville, David C. A., Lachmann, Robin H., Dwek, Raymond A., Butters, Terry D.

Journal:

Biochemical Journal

Année:

2008

Langue:

english

Fichier:

PDF, 186 KB

english, 2008

23

Therapeutic Targets for Inhibitors of Glycosylation

Alonzi, Dominic S., Butters, Terry D.

Journal:

CHIMIA International Journal for Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 272 KB

english, 2011

24

Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals

Caputo, Alessandro T., Alonzi, Dominic S., Marti, Lucia, Reca, Ida-Barbara, Kiappes, J. L., Struwe, Weston B., Cross, Alice, Basu, Souradeep, Lowe, Edward D., Darlot, Benoit, Santino, Angelo, Roversi,

Journal:

Proceedings of the National Academy of Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2016

25

Demonstration that endoplasmic reticulum-associated degradation of glycoproteins can occur downstream of processing by endomannosidase

Kukushkin, Nikolay V., Alonzi, Dominic S., Dwek, Raymond A., Butters, Terry D.

Journal:

Biochemical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 910 KB

english, 2011

26

Urinary glycan markers for disease

Alonzi, Dominic S., Su, Ying-Hsiu, Butters, Terry D.

Journal:

Biochemical Society Transactions

Année:

2011

Langue:

english

Fichier:

PDF, 319 KB

english, 2011

27

Iminosugar antivirals: the therapeutic sweet spot

Alonzi, Dominic S., Scott, Kathryn A., Dwek, Raymond A., Zitzmann, Nicole

Journal:

Biochemical Society Transactions

Année:

2017

Langue:

english

Fichier:

PDF, 840 KB

english, 2017

28

ToP-DNJ, a selective inhibitor of endoplasmic reticulum α-glucosidase II exhibiting anti-flaviviral activity

Kiappes, J.L., Hill, Michelle L., Alonzi, Dominic S, Miller, Joanna L., Iwaki, Ren, Sayce, Andrew C., Caputo, Alessandro T., Kato, Atsushi, Zitzmann, Nicole

Journal:

ACS Chemical Biology

Année:

2017

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2017

29

Amine-linked diglycosides: Synthesis facilitated by the enhanced reactivity of allylic electrophiles, and glycosidase inhibition assays

Cumpstey, Ian, Frigell, Jens, Pershagen, Elias, Akhtar, Tashfeen, Moreno-Clavijo, Elena, Robina, Inmaculada, Alonzi, Dominic S, Butters, Terry D

Journal:

Beilstein Journal of Organic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 402 KB

english, 2011

30

Targeting ER Î±-glucosidase I with a single-dose iminosugar treatment protects against lethal influenza and dengue virus infections

Warfield, Kelly, Alonzi, Dominic S, Hill, Johan, Caputo, Alessandro, Roversi, Pietro, Kiappes, J.L., Sheets, Nicholas, Duchars, Matthew, Dwek, Raymond, Biggins, Julia, Barnard, Dale L., Shresta, Sujan

Journal:

Journal of Medicinal Chemistry

Année:

2020

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2020

31

Structure of human endo-Î±-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

Sobala, Åukasz F., Fernandes, Pearl Z., Hakki, Zalihe, Thompson, Andrew J., Howe, Jonathon D., Hill, Michelle, Zitzmann, Nicole, Davies, Scott, Stamataki, Zania, Butters, Terry D., Alonzi, Dominic S.

Journal:

Proceedings of the National Academy of Sciences

Année:

2020

Fichier:

PDF, 1.30 MB

2020